Motif ID: POU5F1_SOX2{dimer}.p2

Z-value: 0.582


Transcription factors associated with POU5F1_SOX2{dimer}.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1
SOX2 6657 SRY (sex determining region Y)-box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX2chr3_+_181429711-0.344.0e-01Click!
POU5F1chr6_-_31138180-0.117.9e-01Click!


Activity profile for motif POU5F1_SOX2{dimer}.p2.

activity profile for motif POU5F1_SOX2{dimer}.p2


Sorted Z-values histogram for motif POU5F1_SOX2{dimer}.p2

Sorted Z-values for motif POU5F1_SOX2{dimer}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1_SOX2{dimer}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_15940362 1.298 NM_005130
 FGFBP1
fibroblast growth factor binding protein 1
chr4_+_77610610 0.571 SHROOM3
shroom family member 3
chr3_-_56809594 0.537 NM_001128616
 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr2_-_161056573 0.516 NM_000888
 ITGB6
integrin, beta 6
chr15_+_40509628 0.491 NM_001128628
NM_001128629
 PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr12_-_123187842 0.483 NM_177551
 HCAR2
hydroxycarboxylic acid receptor 2
chr2_-_161056762 0.480 ITGB6
integrin, beta 6
chr18_+_61420276 0.478 NM_001040147
 SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr13_-_86373328 0.461 NM_032229
 SLITRK6
SLIT and NTRK-like family, member 6
chr12_-_50616425 0.414 NM_001113547
 LIMA1
LIM domain and actin binding 1
chr4_+_77356252 0.397 NM_020859
 SHROOM3
shroom family member 3
chr12_-_123201319 0.366 NM_006018
 HCAR3
hydroxycarboxylic acid receptor 3
chr17_-_46608271 0.359 NM_002144
 HOXB1
homeobox B1
chr7_+_89843133 0.319 NM_001040666
 STEAP2
STEAP family member 2, metalloreductase
chr8_+_32579350 0.309 NM_001159996
 NRG1
neuregulin 1
chr5_+_140254930 0.298 NM_018903
NM_031864
 PCDHA12

protocadherin alpha 12

chr1_-_177133950 0.284 NM_004319
NM_207108
 ASTN1

astrotactin 1

chr2_+_90077732 0.279


chr4_+_40198526 0.278 NM_004310
 RHOH
ras homolog gene family, member H
chr5_+_76114881 0.276 F2RL1
coagulation factor II (thrombin) receptor-like 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.32 1.71e-05 GO:0006955 immune response
1.96 4.14e-05 GO:0002376 immune system process
1.92 4.69e-02 GO:0007155 cell adhesion
1.92 4.69e-02 GO:0022610 biological adhesion

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.29 1.05e-02 GO:0009986 cell surface
1.81 2.51e-04 GO:0005887 integral to plasma membrane
1.80 2.47e-04 GO:0031226 intrinsic to plasma membrane
1.76 5.86e-03 GO:0044421 extracellular region part
1.66 8.00e-06 GO:0044459 plasma membrane part
1.60 2.44e-04 GO:0005576 extracellular region
1.34 2.10e-03 GO:0005886 plasma membrane
1.34 2.17e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.65 8.18e-04 GO:0004872 receptor activity
1.61 3.85e-02 GO:0004888 transmembrane receptor activity
1.52 5.98e-03 GO:0004871 signal transducer activity
1.52 5.98e-03 GO:0060089 molecular transducer activity