• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: POU5F1_SOX2{dimer}.p2

Z-value: 0.582

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_-_15940362	1.298	NM_005130	FGFBP1	fibroblast growth factor binding protein 1
chr4_+_77610610	0.571		SHROOM3	shroom family member 3
chr3_-_56809594	0.537	NM_001128616	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3
chr2_-_161056573	0.516	NM_000888	ITGB6	integrin, beta 6
chr15_+_40509628	0.491	NM_001128628 NM_001128629	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6
chr12_-_123187842	0.483	NM_177551	HCAR2	hydroxycarboxylic acid receptor 2
chr2_-_161056762	0.480		ITGB6	integrin, beta 6
chr18_+_61420276	0.478	NM_001040147	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr13_-_86373328	0.461	NM_032229	SLITRK6	SLIT and NTRK-like family, member 6
chr12_-_50616425	0.414	NM_001113547	LIMA1	LIM domain and actin binding 1
chr4_+_77356252	0.397	NM_020859	SHROOM3	shroom family member 3
chr12_-_123201319	0.366	NM_006018	HCAR3	hydroxycarboxylic acid receptor 3
chr17_-_46608271	0.359	NM_002144	HOXB1	homeobox B1
chr7_+_89843133	0.319	NM_001040666	STEAP2	STEAP family member 2, metalloreductase
chr8_+_32579350	0.309	NM_001159996	NRG1	neuregulin 1
chr5_+_140254930	0.298	NM_018903 NM_031864	PCDHA12	protocadherin alpha 12
chr1_-_177133950	0.284	NM_004319 NM_207108	ASTN1	astrotactin 1
chr2_+_90077732	0.279
chr4_+_40198526	0.278	NM_004310	RHOH	ras homolog gene family, member H
chr5_+_76114881	0.276		F2RL1	coagulation factor II (thrombin) receptor-like 1
chr2_+_169659099	0.266	NM_001039724 NM_001171632 NM_052946	NOSTRIN	nitric oxide synthase trafficker
chr2_+_204801453	0.264	NM_012092	ICOS	inducible T-cell co-stimulator
chr1_+_32050510	0.263		TINAGL1	tubulointerstitial nephritis antigen-like 1
chr4_+_140586921	0.259	NM_001204366 NM_001204367 NM_001204368 NM_002413	MGST2	microsomal glutathione S-transferase 2
chrY_-_2655478	0.257	NM_003140	SRY	sex determining region Y
chr20_-_6104056	0.247	NM_017671	FERMT1	fermitin family member 1
chr12_-_8815370	0.232	NM_003480	MFAP5	microfibrillar associated protein 5
chr4_+_69313166	0.225	NM_014058	TMPRSS11E	transmembrane protease, serine 11E
chr9_-_140196702	0.222	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr5_+_76114832	0.221	NM_005242	F2RL1	coagulation factor II (thrombin) receptor-like 1
chr9_+_21409132	0.213	NM_002170	IFNA8	interferon, alpha 8
chr6_-_136788012	0.206	NM_001198615	MAP7	microtubule-associated protein 7
chr5_+_140247767	0.206	NM_018902 NM_031861	PCDHA11	protocadherin alpha 11
chr2_-_215896809	0.206	NM_015657	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12
chr2_-_75062214	0.202
chr18_-_28622624	0.199	NM_001941 NM_024423	DSC3	desmocollin 3
chrX_+_2958274	0.192	NM_001201538	ARSF	arylsulfatase F
chr9_-_33465191	0.189		NOL6	nucleolar protein family 6 (RNA-associated)
chr4_-_187644983	0.189	NM_005245	FAT1	FAT tumor suppressor homolog 1 (Drosophila)
chr1_-_42501573	0.189		HIVEP3	human immunodeficiency virus type I enhancer binding protein 3
chr5_+_140207562	0.183	NM_018909 NM_031848 NM_031849	PCDHA6	protocadherin alpha 6
chr10_-_5446781	0.180	NM_001171864 NM_024803	TUBAL3	tubulin, alpha-like 3
chr11_+_112047088	0.178	NM_001037290	BCO2	beta-carotene oxygenase 2
chr12_-_28124915	0.177	NM_002820 NM_198965	PTHLH	parathyroid hormone-like hormone
chr8_+_39771327	0.170	NM_002164	IDO1	indoleamine 2,3-dioxygenase 1
chr5_-_176836488	0.169		F12	coagulation factor XII (Hageman factor)
chr7_-_92855780	0.169	NM_001039372	HEPACAM2	HEPACAM family member 2
chr12_-_6484389	0.168	NM_001159576	SCNN1A	sodium channel, nonvoltage-gated 1 alpha
chr9_+_71944240	0.168	NM_004816	FAM189A2	family with sequence similarity 189, member A2
chr1_-_217250230	0.168	NM_001243507 NM_001243509	ESRRG	estrogen-related receptor gamma
chr5_-_64777703	0.167	NM_197941	ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr10_-_123356158	0.164	NM_001144915	FGFR2	fibroblast growth factor receptor 2
chr12_-_105322056	0.163	NM_032148	SLC41A2	solute carrier family 41, member 2
chr12_+_20963637	0.161	NM_019844	SLCO1B3	solute carrier organic anion transporter family, member 1B3
chr7_-_16505292	0.158	NM_015464	SOSTDC1	sclerostin domain containing 1
chr2_+_113885137	0.155	NM_173842	IL1RN	interleukin 1 receptor antagonist
chr2_+_183608329	0.154		DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10
chr3_+_189507448	0.151	NM_001114980 NM_001114981 NM_001114982	TP63	tumor protein p63
chr4_+_140587086	0.149		MGST2	microsomal glutathione S-transferase 2
chr18_+_29027731	0.147	NM_001944	DSG3	desmoglein 3
chr7_+_47694841	0.147	NM_001123065	C7orf65	chromosome 7 open reading frame 65
chr12_-_10021932	0.145		CLEC2B	C-type lectin domain family 2, member B
chr1_+_87012758	0.144	NM_012128	CLCA4	chloride channel accessory 4
chr6_-_138820578	0.138	NM_001144060	NHSL1	NHS-like 1
chr12_-_8815266	0.135		MFAP5	microfibrillar associated protein 5
chrM_+_9217	0.135
chr1_+_167298382	0.135		POU2F1	POU class 2 homeobox 1
chrM_+_8857	0.132
chr7_-_16844606	0.132	NM_006408	AGR2	anterior gradient 2 homolog (Xenopus laevis)
chr14_-_106641585	0.129		IGHV4-31 IGHA1 IGHA2 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_-_47473424	0.128	NM_001143668 NM_181847	AMIGO2	adhesion molecule with Ig-like domain 2
chr5_+_173472737	0.128		HMP19	HMP19 protein
chr10_+_7745325	0.128		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr4_-_123542165	0.127	NM_001207006 NM_021803	IL21	interleukin 21
chr6_-_11779279	0.127	NM_001143948 NM_032744	C6orf105	chromosome 6 open reading frame 105
chr20_+_18794369	0.127	NM_178483	C20orf79	chromosome 20 open reading frame 79
chr4_-_68411234	0.126	NM_001812	CENPC1	centromere protein C 1
chr5_-_176836535	0.125	NM_000505	F12	coagulation factor XII (Hageman factor)
chr12_+_50869531	0.124		LARP4	La ribonucleoprotein domain family, member 4
chr12_+_41831484	0.122	NM_013377	PDZRN4	PDZ domain containing ring finger 4
chr4_+_70796798	0.122	NM_001025104 NM_001890	CSN1S1	casein alpha s1
chr21_-_43346780	0.121	NM_199050	C2CD2	C2 calcium-dependent domain containing 2
chr4_-_68411189	0.121		CENPC1	centromere protein C 1
chrX_+_144908927	0.121	NM_004709	CXorf1	chromosome X open reading frame 1
chrM_+_9182	0.120
chr19_-_57678855	0.120	NM_001012729	DUXA	double homeobox A
chr3_+_156008775	0.119	NM_172159	KCNAB1	potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr7_-_139763520	0.116	NM_022750	PARP12	poly (ADP-ribose) polymerase family, member 12
chr6_+_32407618	0.114	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr9_-_104145800	0.111	NM_001127610	BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr11_-_112034671	0.111	NM_001243211 NM_001562	IL18	interleukin 18 (interferon-gamma-inducing factor)
chr17_-_64225496	0.110	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr19_+_21264952	0.109	NM_182515	ZNF714	zinc finger protein 714
chr7_+_26400503	0.109	NM_001199837	SNX10	sorting nexin 10
chr1_-_24239758	0.109	NM_001841	CNR2	cannabinoid receptor 2 (macrophage)
chr2_+_102979096	0.108	NM_003855	IL18R1	interleukin 18 receptor 1
chr14_-_107170076	0.104		IGHV1-69 IGHG1	immunoglobulin heavy variable 1-69 immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_+_7864049	0.102	NM_199286	DPPA3 STELLAR	developmental pluripotency associated 3 developmental pluripotency associated 3 pseudogene
chr10_+_7745284	0.102		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr2_+_113885145	0.100		IL1RN	interleukin 1 receptor antagonist
chr13_-_48987017	0.099		LPAR6	lysophosphatidic acid receptor 6
chr11_+_112046207	0.099	NM_031938	BCO2	beta-carotene oxygenase 2
chr10_-_73848766	0.098	NM_001134434 NM_014767	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr17_-_29641087	0.097		EVI2B	ecotropic viral integration site 2B
chr10_+_7745229	0.096	NM_002216	ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr3_+_121774208	0.095	NM_001206924 NM_001206925 NM_175862	CD86	CD86 molecule
chr1_+_61542790	0.094
chr12_-_71031174	0.093	NM_001109754	PTPRB	protein tyrosine phosphatase, receptor type, B
chr21_+_43710190	0.093		ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1
chr19_+_42259397	0.092	NM_002483	CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr1_-_54355405	0.092		YIPF1	Yip1 domain family, member 1
chr12_+_25205180	0.091	NM_001204126 NM_001204127 NM_006152	LRMP	lymphoid-restricted membrane protein
chr1_+_16083132	0.091		FBLIM1	filamin binding LIM protein 1
chr1_-_54355472	0.090	NM_018982	YIPF1	Yip1 domain family, member 1
chr12_-_52828105	0.090	NM_004693	KRT75	keratin 75
chr7_+_80267782	0.090	NM_000072 NM_001001548	CD36	CD36 molecule (thrombospondin receptor)
chr10_+_7745354	0.089		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chrX_+_138612894	0.089	NM_000133	F9	coagulation factor IX
chr4_-_41750936	0.088	NM_003924	PHOX2B	paired-like homeobox 2b
chr3_-_196911001	0.088	NM_001204387 NM_001204388	DLG1	discs, large homolog 1 (Drosophila)
chr11_+_124120422	0.088	NM_001002905	OR8G1	olfactory receptor, family 8, subfamily G, member 1
chr3_-_155421996	0.088	NM_014996	PLCH1	phospholipase C, eta 1
chr12_+_25205488	0.087		LRMP	lymphoid-restricted membrane protein
chr7_+_37723378	0.087
chr11_-_16424391	0.087	NM_001145819 NM_017508	SOX6	SRY (sex determining region Y)-box 6
chr10_-_98325100	0.086		TM9SF3	transmembrane 9 superfamily member 3
chrX_+_65235279	0.086
chrX_-_33229428	0.085	NM_004006	DMD	dystrophin
chr14_-_107170400	0.085		IGHV4-31 IGHV1-69 IGHA1 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 1-69 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr20_+_32951054	0.084	NM_031483	ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)
chr2_+_128928040	0.084		UGGT1	UDP-glucose glycoprotein glucosyltransferase 1
chr20_+_9198036	0.083	NM_182797	PLCB4	phospholipase C, beta 4
chr14_-_24423329	0.083		C14orf167	chromosome 14 open reading frame 167
chr1_-_150738292	0.082	NM_001199739 NM_004079	CTSS	cathepsin S
chr13_-_99959649	0.081	NM_004951	GPR183	G protein-coupled receptor 183
chr5_+_140809957	0.080		PCDHGA12	protocadherin gamma subfamily A, 12
chr2_-_219157207	0.080	NM_022152	TMBIM1	transmembrane BAX inhibitor motif containing 1
chr13_-_24007822	0.080	NM_014363	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)
chr11_-_16497917	0.079	NM_033326	SOX6	SRY (sex determining region Y)-box 6
chr6_-_47254143	0.079		TNFRSF21	tumor necrosis factor receptor superfamily, member 21
chr6_+_24357130	0.078	NM_181337	KAAG1	kidney associated antigen 1
chr1_+_35544948	0.077	NM_024772	ZMYM1	zinc finger, MYM-type 1
chr3_-_38835500	0.077	NM_006514	SCN10A	sodium channel, voltage-gated, type X, alpha subunit
chr16_+_76311175	0.077	NM_033401	CNTNAP4	contactin associated protein-like 4
chr6_-_31560497	0.077	NM_001145466 NM_001145467 NM_147130	NCR3	natural cytotoxicity triggering receptor 3
chr14_+_69658193	0.077	NM_001193360 NM_001193361 NM_018199	EXD2	exonuclease 3'-5' domain containing 2
chr5_+_40841296	0.077	NM_032587	CARD6	caspase recruitment domain family, member 6
chr8_-_82395401	0.076	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr7_+_26403944	0.076	NM_001199838	SNX10	sorting nexin 10
chr3_+_97868169	0.076	NM_001005514	OR5H14	olfactory receptor, family 5, subfamily H, member 14
chr2_+_138721807	0.075	NM_001024074 NM_001024075 NM_006895	HNMT	histamine N-methyltransferase
chr8_-_57026540	0.075	NM_005372	MOS	v-mos Moloney murine sarcoma viral oncogene homolog
chrX_+_100474932	0.075	NM_001171184 NM_001939	DRP2	dystrophin related protein 2
chr1_-_32827843	0.073	NM_001167676	LOC100128071	uncharacterized LOC100128071
chr20_-_9819406	0.073	NM_020341 NM_177990	PAK7	p21 protein (Cdc42/Rac)-activated kinase 7
chr6_-_108145507	0.072	NM_198081	SCML4	sex comb on midleg-like 4 (Drosophila)
chrX_+_30261847	0.071	NM_002363 NM_177415	MAGEB1	melanoma antigen family B, 1
chr7_-_55930444	0.071	NM_207366	SEPT14	septin 14
chr1_-_177133818	0.071		ASTN1	astrotactin 1
chr2_+_207406815	0.070		ADAM23	ADAM metallopeptidase domain 23
chr2_-_233641225	0.070	NM_001172416 NM_001172417 NM_002242	KCNJ13	potassium inwardly-rectifying channel, subfamily J, member 13
chr10_-_5045967	0.070	NM_001135241	AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr4_-_111563278	0.070	NM_001204397 NM_001204398 NM_001204399 NM_153426 NM_153427	PITX2	paired-like homeodomain 2
chr2_-_231989755	0.069	NM_000867	HTR2B	5-hydroxytryptamine (serotonin) receptor 2B
chr4_-_122085475	0.069	NM_024873	TNIP3	TNFAIP3 interacting protein 3
chr11_+_131240370	0.069	NM_001048209	NTM	neurotrimin
chr17_+_28268622	0.067	NM_198529	EFCAB5	EF-hand calcium binding domain 5
chr12_-_11214892	0.067	NM_176887	TAS2R46	taste receptor, type 2, member 46
chr2_+_191301020	0.067		MFSD6	major facilitator superfamily domain containing 6
chr15_+_69606741	0.067	NM_001104554	PAQR5	progestin and adipoQ receptor family member V
chr17_-_15523017	0.066	NM_006382	CDRT1	CMT1A duplicated region transcript 1
chr20_+_58533470	0.066	NM_177980	CDH26	cadherin 26
chr1_+_152956563	0.065	NM_001199828 NM_005987	SPRR1A	small proline-rich protein 1A
chr4_+_153864134	0.065	NM_033393	FHDC1	FH2 domain containing 1
chr2_+_113763448	0.064	NM_014440	IL36A	interleukin 36, alpha
chr12_+_21168629	0.064	NM_001009562	SLCO1B7	solute carrier organic anion transporter family, member 1B7 (non-functional)
chr1_-_108786663	0.064	NM_001143989	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chr3_-_101395611	0.063	NM_014415	ZBTB11	zinc finger and BTB domain containing 11
chr21_-_36252872	0.063		RUNX1	runt-related transcription factor 1
chr9_+_2717525	0.062	NM_133497	KCNV2	potassium channel, subfamily V, member 2
chr14_+_69658215	0.062		EXD2	exonuclease 3'-5' domain containing 2
chr12_-_14996381	0.062	NM_021071	ART4	ADP-ribosyltransferase 4 (Dombrock blood group)
chr18_-_61329113	0.061	NM_006919	SERPINB3	serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr10_-_75193297	0.061	NM_001024593	ZMYND17	zinc finger, MYND-type containing 17
chr3_+_97851540	0.060	NM_001005338	OR5H1	olfactory receptor, family 5, subfamily H, member 1
chr3_+_108021331	0.060	NM_007072	HHLA2	HERV-H LTR-associating 2
chr2_-_97405799	0.060	NM_001142292 NM_030805	LMAN2L	lectin, mannose-binding 2-like
chr11_-_35441501	0.060	NM_001195728 NM_001252652	SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr17_-_48945338	0.060	NM_001243877	TOB1	transducer of ERBB2, 1
chr13_-_28543290	0.060	NM_001265	CDX2	caudal type homeobox 2
chr6_-_32784727	0.059	NM_002120	HLA-DOB	major histocompatibility complex, class II, DO beta
chr7_+_136553398	0.059	NM_001006627 NM_001006630	CHRM2	cholinergic receptor, muscarinic 2
chr1_-_115238091	0.059	NM_000036 NM_001172626	AMPD1	adenosine monophosphate deaminase 1
chr10_-_116418056	0.058	NM_002313	ABLIM1	actin binding LIM protein 1
chr14_+_32798478	0.057	NM_004274	AKAP6	A kinase (PRKA) anchor protein 6
chr14_-_106774311	0.057		IGHA1	immunoglobulin heavy constant alpha 1
chr19_-_5838740	0.057		FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
chr14_-_35344852	0.056	NM_013448 NM_182648	BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chr10_+_91498724	0.056		KIF20B	kinesin family member 20B
chr19_-_48389514	0.056		SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.32	1.71e-05	GO:0006955	immune response
1.96	4.14e-05	GO:0002376	immune system process
1.92	4.69e-02	GO:0007155	cell adhesion
1.92	4.69e-02	GO:0022610	biological adhesion

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.66	8.00e-06	GO:0044459	plasma membrane part
1.60	2.44e-04	GO:0005576	extracellular region
1.80	2.47e-04	GO:0031226	intrinsic to plasma membrane
1.81	2.51e-04	GO:0005887	integral to plasma membrane
1.34	2.10e-03	GO:0005886	plasma membrane
1.34	2.17e-03	GO:0071944	cell periphery
1.76	5.86e-03	GO:0044421	extracellular region part
2.29	1.05e-02	GO:0009986	cell surface

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.65	8.18e-04	GO:0004872	receptor activity
1.52	5.98e-03	GO:0004871	signal transducer activity
1.52	5.98e-03	GO:0060089	molecular transducer activity
1.61	3.85e-02	GO:0004888	transmembrane receptor activity